*** Regular expression operations and buffer string searches now
convert the search pattern to multibyte or unibyte to accord with the buffer or string being searched.

One consequence is that you cannot always use \200-\377 inside of [...] to match all non-ASCII characters. This does still work when searching or matching a unibyte buffer or string, but not when searching or matching a multibyte string. Unfortunately, there is no obvious choice of syntax to use within [...] for that job. But, what you want is just to match all non-ASCII characters, the regular expression [^\0-\177] works for it.